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The triage role of cytological DNA methylation in women with non-16/18, specifically genotyping high-risk HPV infection

10 Apr 2025

Abstract excerpt

OBJECTIVES: To evaluate cytological DNA methylation testing methods for risk stratification in women with non-16/18 HPV, focusing on high-risk HPV (hrHPV) genotyping. METHODS: This study compared the triage performance of liquid-based cytology (LBC) testing, hrHPV genotyping, and PAX1/JAM3 gene methylation (CISCER) testing. The absolute risks of cervical intraepithelial neoplasia grade 2 or worse (CIN2+), grade 3...

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PMID: 40204948
DOI: 10.1038/s41416-025-03005-5

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