Article
PAX1/SOX1 DNA Methylation Versus Cytology and HPV16/18 Genotyping for the Triage of High-Risk HPV-Positive Women in Cervical Cancer Screening: Retrospective Analysis of Archival Samples.
BJOG : an international journal of obstetrics and gynaecology - 1 Jan 2025
Chan Karen K L, Liu Stephanie S, Lau Lesley S K, Ngu Siew Fei, Chu Mandy M Y, Tse K Y, Cheung Annie N Y, Ngan Hextan Y S
Abstract excerpt
OBJECTIVE: To compare the performance of cytology, HPV16/18 genotyping and PAX1/SOX1 methylation for the triage of high-risk HPV-positive cervical samples. DESIGN: Retrospective analyses of archival samples collected from a large-scale prospective randomised controlled trial. SETTING/SAMPLE: HPV-positive women recruited from the general cervical screening population. METHODS: 403 HPV-positive samples including...
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