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Article

Characterization of quasispecies of severe fever with thrombocytopenia syndrome virus.

Journal of virology - 20 May 2025

Lokupathirage Sithumini M W, Muthusinghe Devinda S, Sarii Rakiiya S, Akanbi Olusola A, Shimizu Kenta, Tsuda Yoshimi, Yoshimatsu Kumiko

Abstract excerpt

Three specific amino acid variations have been identified in the quasispecies of the isolated YG1 strain of severe fever with thrombocytopenia syndrome virus (SFTSV): Gn (Y328H), Gc (R624W), and L (N1891K). The Gn (Y328H) accounted for 26.9% of the viruses in the patient's blood. The other two mutations are less frequent, indicating that these mutations appeared during propagation in Vero E6 cells. To investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40202315
DOI: 10.1128/jvi.01794-24
PMCID: PMC12090785

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CPE

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