Article
Genetic Susceptibility Is One of the Determinants for Severe Fever with Thrombocytopenia Syndrome Virus Infection and Fatal Outcome: An Epidemiological Investigation.
PloS one - 1 Jan 2015
Sun Jimin, Tang Yuming, Ling Feng, Chang Yue, Ye Xiaohong, Shi Wen, Zhang Lei, Chen Zhiping, Lin Haijiang, Qiu Zaiping, Zhang Yanjun, Zhang Rong, Mao Haiyan, Chen Enfu, Lin Junfen, Jiang Jianmin, Xia Shichang, Gong Zhenyu
Abstract excerpt
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in China and case-fatality rate of SFTS is very high (approximately 10%). However, genetic susceptibility for SFTS virus (SFTSV) infection and fatal outcome of SFTSV infection in humans are unclear. In this study, we investigated the clinical, laboratory and epidemiological features of SFTS in a cluster of three sisters who died...
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