Stratification of human gut microbiomes by succinotype is associated with inflammatory bowel disease status

Abstract excerpt

BACKGROUND: The human gut microbiome produces and consumes a variety of compounds that interact with the host and impact health. Succinate is of particular interest as it intersects with both host and microbiome metabolism. However, which gut bacteria are most responsible for the consumption of intestinal succinate is poorly understood. RESULTS: We build upon an enrichment-based whole fecal sample culturing...

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