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Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis

15 Sept 2023

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a complex, fatal neurodegenerative disease. Disease pathophysiology is incompletely understood but evidence suggests gut dysbiosis occurs in ALS, linked to impaired gastrointestinal integrity, immune system dysregulation and altered metabolism. Gut microbiome and plasma metabolome have been separately investigated in ALS, but little is known about gut microbe-plasma...

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PMID: 37721161
DOI: 10.1093/brain/awad306

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