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Article

Impacts of high mobility group box protein 1 gene polymorphisms on morbidity and mortality after living donor liver transplantation.

Transplant immunology - 1 May 2025

Tsukiyama Naofumi, Tanaka Yuka, Yamane Hiroaki, Tanimine Naoki, Kuroda Shintaro, Tahara Hiroyuki, Ohira Masahiro, Ide Kentaro, Kobayashi Tsuyoshi, Ohdan Hideki

Abstract excerpt

We investigated the effect of single-nucleotide polymorphisms (SNPs) in the high mobility group box 1 (HMGB1) gene on morbidity and mortality after liver transplantation (LT). Among 120 LT recipients and their living donors, the genotypes of HMGB1, and the SNPs rs2249825, rs1045411, rs1412125, and rs1360485 were determined. There were no significant associations between these four SNPs and the incidence of...

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Identifiers

PMID: 40157616
DOI: 10.1016/j.trim.2025.102225

Genes

HMGB1
GC

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