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Biological characteristics and transcriptomic profile of adipose-derived mesenchymal stem cells isolated from prion-infected murine model

28 Mar 2025

Abstract excerpt

BACKGROUND: levels following inoculation, raising concerns regarding their safe and effective use in medical applications. Prion infectivity has been reported in fat tissues, thus the response of adipose-derived MSCs (AdMSCs) to prion infection needs to be fully studied. METHODS: For this study, we analyzed the properties of AdMSCs isolated from mice infected with the ME7 scrapie strain and compared them with...

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PMID: 40156048
DOI: 10.1186/s13287-025-04273-x

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