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Programmed cell death-related prognostic genes mediate dysregulation of the immune microenvironment in triple-negative breast cancer

12 Mar 2025

Abstract excerpt

Background: Programmed Cell death (PCD) encompasses a spectrum of genetically regulated cell death processes and plays a double-edged sword role in neoplastic progression and therapeutic resistance of Triple-Negative Breast Cancer(TNBC)through the tumor microenvironment (TME). However, the specific mechanisms by which PCD mediates microenvironmental dysregulation remain elusive. Methods: Analyzing nine samples of...

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PMID: 40145099
DOI: 10.3389/fimmu.2025.1563630

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