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Single-cell transcriptomic analysis reveals CD8 + T cell heterogeneity and identifies a prognostic signature in cervical cancer

18 Mar 2025

Abstract excerpt

BACKGROUND: In recent years, immunotherapy has made significant progress. However, the understanding of the heterogeneity and function of T cells, particularly CD8 + T cells, in cervical cancer (CESC) microenvironment remains insufficient. We aim to characterize the heterogeneity, developmental trajectory, regulatory network, and intercellular communication of CD8 + T cells in cervical squamous cell carcinoma and...

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PMID: 40102789
DOI: 10.1186/s12885-025-13901-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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