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Tumor microenvironment variation implicates immune alterations and correlates with prognosis in patients with glioma

2024-01-05

Abstract excerpt

To investigate the microenvironment composition of gliomas and the associated clinical significance, we analyzed single-cell RNA sequencing and bulk RNA-seq data from glioma samples. Cell trajectory analysis identified five trajectories with distinct cell states and corresponding trajectory-related genes (TRGs). TRG-based clustering segregated patients with glioma with different overall survival, clinicopathologic...

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Literature Corpus work
2cac61d2-25cf-5b3e-b8d5-38e02b023dd2
DOI
10.21203/rs.3.rs-3829624/v1
Open publication

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Tumor microenvironment variation implicates immune alterations and correlates with prognosis in patients with gliomaDOI 10.21203/rs.3.rs-3829624/v1
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