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Mitochondrial Regulation of Ferroptosis in Cancer Cells

24 Feb 2025

Abstract excerpt

Ferroptosis is an iron-dependent nonapoptotic regulated cell death modality characterized by lethal levels of lipid peroxide accumulation and disrupted antioxidant systems. An increasing number of studies have revealed correlations between ferroptosis and the pathophysiology and treatment of cancer. Given the intricate involvement of mitochondria in ferroptosis, as suggested by previous studies, here, we review...

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PMID: 40083691
DOI: 10.7150/ijbs.105446

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