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Article

Real-world treatment patterns and outcomes based on RAS/BRAF status in metastatic colorectal cancer-Analysis of the Prospective Dutch Colorectal Cancer cohort.

International journal of cancer - 1 Aug 2025

van Nassau Sietske C M W, Zwart Koen, van der Baan Frederieke H, Vink Geraldine R, Elferink Marloes A G, Snaebjornsson Petur, May Anne M, Koopman Miriam, Roodhart Jeanine M L

Abstract excerpt

The treatment landscape for metastatic colorectal cancer (mCRC) has evolved into a continuum of care with an essential role for biomarkers and molecular subgroups. Treatment guidelines are primarily based on trial results; however, populations and outcomes differ from clinical practice. To support the interpretation of trial results and to assist in tailored patient counseling, we evaluated real-world treatment...

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Identifiers

PMID: 40081858
DOI: 10.1002/ijc.35410
PMCID: PMC12141976

Genes

BRAF

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