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Article

Thyroid Function and Mood Disorders: A Mendelian Randomization Study

24 Apr 2021

Abstract excerpt

Background: Observational studies suggest that even minor variations in thyroid function are associated with the risk of mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD). However, it is unknown whether these associations are causal or not. We used a Mendelian randomization (MR) approach to investigate causal effects of minor variations in thyrotropin (TSH) and free thyroxine...

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Genetic Associations and Epidemiology
Genetics and Neurodevelopmental Disorders
Thyroid Disorders and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33899528
DOI: 10.1089/thy.2020.0884

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