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Article

Does autoimmune diseases increase the risk of frailty? A Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Zhou Jinlei, Zhang Yuan, Ni Ting, Li Yanlei, Shao Haiyu, Wang Fei, Xu Sen, Huang Yazeng, Zhang Jun, Zhao Tingxiao

Abstract excerpt

Background: The causality of autoimmune diseases with frailty has not been firmly established. We conducted this Mendelian randomization (MR) study to unveil the causal associations between autoimmune diseases with frailty. Methods: A MR analyses were performed to explore the relationships between autoimmune disease and frailty, using summary genome-wide association statistics. Results: Through a comprehensive...

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Autoimmune Diseases
Frailty
Genetic Predisposition to Disease
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39257904
DOI: 10.3389/fendo.2024.1364368
PMCID: PMC11384993

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