Article
Gut Microbiome and Stroke: a Bidirectional Mendelian Randomisation Study in East Asian and European Populations.
Stroke and vascular neurology - 30 Dec 2024
Cheng Shiyao, Zheng Hao, Wei Yuandan, Lin Xingchen, Gu Yuqin, Guo Xinxin, Fan Zhe, Li Hao, Cheng Si, Liu Siyang
Abstract excerpt
BACKGROUND AND AIMS: Observational studies have implicated the involvement of gut microbiome in stroke development. Conversely, stroke may disrupt the gut microbiome balance, potentially causing systemic infections exacerbated brain infarction. However, the causal relationship remains controversial or unknown. To investigate bidirectional causality and potential ethnic differences, we conducted a bidirectional...
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