Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of PTEN Mutations in Fine Needle Aspiration Biopsies of Indeterminate Thyroid Nodules: Impact on Diagnosis and Prognosis.

Head & neck - 1 Aug 2025

Schlegel Lauren E, Brill-Edwards Madelaine, Wang Zi-Xuan, McNair Christopher, Gargano Stacey, Cottrill Elizabeth

Abstract excerpt

BACKGROUND: Data connecting PTEN mutations with thyroid cancer risk for indeterminate nodules remain limited due to the rare nature of these mutations. The aim of this study was to determine the relationship between PTEN mutations identified in cytologically indeterminate nodules and final pathology and clinical outcomes. METHODS: This 8-year retrospective study includes adults with indeterminate thyroid nodules...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Prognosis

Share to PTEN Phosphohydrolase

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Share to Thyroid Nodule

Source

Open in PubMed Open full text

Identifiers

PMID: 40055996
DOI: 10.1002/hed.28127
PMCID: PMC12248271

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of PTEN Mutations in Fine Needle Aspiration Biopsies of Indeterminate Thyroid Nodules: Impact on Diagnosis and Prognosis.PMID 40055996Read ↗

Clinicopathologic features of thyroid nodules with PTEN mutations on preoperative testing.Semantic proximity Read ↗

Next generation sequence-based targeted somatic mutation analysis in thyroid nodules with pathologically diagnosed as indeterminate cytology.Semantic proximity Read ↗

Molecular diagnosis for indeterminate thyroid nodules on fine needle aspiration: advances and limitations.Semantic proximity Read ↗

Overview of molecular biomarkers for enhancing the management of cytologically indeterminate thyroid nodules and thyroid cancer.Semantic proximity Read ↗

Next Generation Sequence-Based Targeted Somatic Mutation Analysis in Thyroid Nodules with Pathologically Diagnosed as Indeterminate CytologySemantic proximity Read ↗

Cytologic atypia is predictive of increased risk of malignancy and BRAF mutations in thyroid follicular neoplasms (Bethesda category IV).Semantic proximity Read ↗

Preoperative Role of RAS or BRAF K601E in the Guidance of Surgery for Indeterminate Thyroid Nodules.Semantic proximity Read ↗

Contribution of molecular testing to thyroid fine-needle aspiration cytology of "follicular lesion of undetermined significance/atypia of undetermined significance".Semantic proximity Read ↗

Correlation between indeterminate aspiration cytology and final histopathology of thyroid neoplasms.Semantic proximity Read ↗

BRAF mutation detection in indeterminate thyroid cytology specimens: underlying cytologic, molecular, and pathologic characteristics of papillary thyroid carcinoma.Semantic proximity Read ↗

BRAF-mutated carcinomas among thyroid nodules with prior indeterminate FNA report: a systematic review and meta-analysis.Semantic proximity Read ↗

Clinical performance of multiplatform mutation panel and microRNA risk classifier in indeterminate thyroid nodules.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.