Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of mitochondria-related key gene and association with immune cells infiltration in intervertebral disc degeneration

8 Mar 2023

Abstract excerpt

Intervertebral disc (IVD) degeneration and its inflammatory microenvironment can result in discogenic pain, which has been shown to stem from the nucleus pulposus (NP). Increasing evidence suggests that mitochondrial related genes are strictly connected to cell functionality and, importantly, it can regulate cell immune activity in response to damaged associated signals. Therefore, identification of mitochondria...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Musculoskeletal pain and rehabilitation
Share to Spine and Intervertebral Disc Pathology
Share to Spondyloarthritis Studies and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36968589
DOI: 10.3389/fgene.2023.1135767

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of mitochondria-related key gene and association with immune cells infiltration in intervertebral disc degenerationPMID 36968589Read ↗

Identification of Core Genes and Screening of Potential Targets in Intervertebral Disc Degeneration Using Integrated Bioinformatics AnalysisSemantic proximity Read ↗

Revealing the Immune Infiltration Landscape and Identifying Diagnostic Biomarkers for Lumbar Disc HerniationSemantic proximity Read ↗

Identification and Functional Validation of ACSL1 as a Biomarker Regulating Ferroptosis in Nucleus Pulposus CellSemantic proximity Read ↗

Identification and functional validation of ACSL1 as a biomarker regulating ferroptosis in nucleus pulposus cellSemantic proximity Read ↗

Single-Cell and WGCNA Integrative Analysis Reveal the Key Chondrocytes Niches and Pathogenic Genes in Intervertebral Disc DegenerationSemantic proximity Read ↗

Integrative Bioinformatics Analysis Revealed Mitochondrial Dysfunction‐Related Genes Underlying Intervertebral Disc DegenerationSemantic proximity Read ↗

Integrating bioinformatics and experimental validation to Investigate IRF1 as a novel biomarker for nucleus pulposus cells necroptosis in intervertebral disc degenerationSemantic proximity Read ↗

Identification of core genes in intervertebral disc degeneration using bioinformatics and machine learning algorithmsSemantic proximity Read ↗

Comprehensive bioinformatics analyses reveal immune genes responsible for altered immune microenvironment in intervertebral disc degenerationSemantic proximity Read ↗

Development of a Novel Inflammatory‐Associated Gene Signature and Immune Infiltration Patterns in Intervertebral Disc DegenerationSemantic proximity Read ↗

Integration of single-cell and transcriptome sequencing data reveals the mechanism of macrophage polarization-related genes in intervertebral disc degenerationSemantic proximity Read ↗

Identification and validation of ferroptosis-related gene signature in intervertebral disc degenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.