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Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study.

Aging - 25 Feb 2025

Fricke Deidra R, Cvejkus Ryan K, Barinas-Mitchell Emma, Feitosa Mary F, Murabito Joanne M, Acharya Sandeep, Brent Michael R, Daw E Warwick, Minster Ryan L, Zmuda Joseph M, Kuipers Allison L

Abstract excerpt

Peripheral artery disease (PAD) is a major contributor to morbidity in older adults. We aimed to determine genetic and non-genetic determinants of PAD and ankle-brachial index (ABI) in the Long Life Family Study (LLFS). 3006 individuals had ABI assessment, including 1090 probands (mean age 89), 1554 offspring (mean age 60) and 362 spousal controls (mean age 61). Outcomes include minimum of right and left ABIs and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40013929
DOI: 10.18632/aging.206204
PMCID: PMC11892930

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DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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