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Evolutionary Mechanisms of the Emergence of the Variants of Concern of SARS-CoV-2

30 Jan 2025

Abstract excerpt

The evolutionary origin of the variants of concern (VOCs) of SARS-CoV-2, characterized by a large number of new substitutions and strong changes in virulence and transmission rate, is intensely debated. The leading explanation in the literature is a chronic infection in immunocompromised individuals, where the virus evolves before returning into the main population. The present article reviews less-investigated...

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PMID: 40006952
DOI: 10.3390/v17020197

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