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Article

TP53 Deficiency in the Natural History of Prostate Cancer

14 Feb 2025

Abstract excerpt

Prostate cancer remains a leading cause of cancer-related mortality in men, with advanced stages posing significant treatment challenges due to high morbidity and mortality. Among genetic alterations, TP53 mutations are among the most prevalent in cancers and are strongly associated with poor clinical outcomes and therapeutic resistance. This review investigates the role of TP53 mutations in prostate cancer...

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PMID: 40002239
DOI: 10.3390/cancers17040645

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