Article
Liquid biopsy in prostate cancer: A novel dual biomarker analysis approach integrating circulating tumor cells and circulating tumor DNA data.
Cellular and molecular biology (Noisy-le-Grand, France) - 8 Sept 2024
Li Qianyue, Tang Lei, Zhao Yawei, Li Zhikun, Ma Wang, Ma Liujiang
Abstract excerpt
This study aimed to explore the potential of liquid biopsy as a diagnostic tool by integrating two key biomarkers, Circulating Tumor Cells (CTCs) and Circulating Tumor DNA (ctDNA), and to enhance the detection fidelity of prostate cancer. A dual biomarker analysis approach was employed to synergize the sensitivities of CTCs and ctDNA. Various genetic mutations of ctDNA and tissues were scrutinized, investigating...
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