Article
The two-step model of bacterial UV mutagenesis.
Mutation research - 1 Jan 2000
Bridges B A, Woodgate R
Abstract excerpt
Recent results are discussed which have led to a two-step model for UV mutagenesis in excision-deficient Escherichia coli. After exposure to UV, the replication fork is assumed to continue until immediately before certain photoproducts where it stops and leaves a gap which cannot be dealt with by...
Topics
- Bacteria
- Bacterial Proteins
- DNA Repair
- Deoxyribodipyrimidine Photo-Lyase
- Models, Biological
- Mutation
- Rec A Recombinases
- Serine Endopeptidases
- Ultraviolet Rays
