Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis.

Current allergy and asthma reports - 1 Sept 2010

Martinez-Moczygemba Margarita, Huston David P

Abstract excerpt

Pulmonary alveolar proteinosis (PAP) is a rare disease of the lung characterized by the accumulation of surfactant-derived lipoproteins within pulmonary alveolar macrophages and alveoli, resulting in respiratory insufficiency and increased infections. The disease is caused by a disruption in surf...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Specificity
Share to Antibodies, Neutralizing
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins

Share to Macrophages, Alveolar

Share to Pulmonary Alveolar Proteinosis

Share to Pulmonary Alveoli

Share to Receptors, Granulocyte-Macrophage Colony-Stimulating Factor

Source

Identifiers

PMID: 20623372
DOI: 10.1007/s11882-010-0134-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20623372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis.PMID 20623372Read ↗

Pulmonary alveolar proteinosis.Semantic proximity Read ↗

Pathogenesis-driven treatment of primary pulmonary alveolar proteinosis.Semantic proximity Read ↗

Pulmonary alveolar proteinosis.Semantic proximity Read ↗

Out of breath: GM-CSFRalpha mutations disrupt surfactant homeostasis.Semantic proximity Read ↗

Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy.Semantic proximity Read ↗

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.Semantic proximity Read ↗

Pulmonary alveolar proteinosis: a review.Semantic proximity Read ↗

Targeted therapy for pulmonary alveolar proteinosis: the time is nowSemantic proximity Read ↗

Elderly-onset hereditary pulmonary alveolar proteinosis and its cytokine profile.Semantic proximity Read ↗

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1.Semantic proximity Read ↗

Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function.Semantic proximity Read ↗

Evaluating the evidence for GM-CSF as a host-directed therapy in respiratory infectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.