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Article

Somatic Genomic Profiling of Pancreatic Ductal Adenocarcinomas From a Diverse Cohort of Patients.

Pancreas - 1 Mar 2025

Riner Andrea N, Velazquez-Villarreal Enrique I, Rajpara Seeta, Qian Jing, Jin Yuxin, Loza Donna, Akki Ashwin, Herremans Kelly M, Raj Rohit, Williams Terence M, Merchant Nipun, George Thomas J, Hughes Steven J, Stern Mariana C, Reams Renee, Redda Ken, Wilkie Diana J, Odedina Folakemi T, Chamala Srikar, Han Bo, Agyare Edward, Craig David W, Carpten John D, Trevino Jose G

Abstract excerpt

OBJECTIVES: Black/African American (B/AA) pancreatic ductal adenocarcinoma (PDAC) patients have worse clinical outcomes than White patients and are underrepresented in genomic databases. We aimed to expand our understanding of the PDAC somatic landscape from a diverse cohort. MATERIALS AND METHODS: Formalin-fixed paraffin-embedded specimens from 24 surgically resected PDAC cases were collected, with self-reported...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39999309
DOI: 10.1097/MPA.0000000000002408
PMCID: PMC12203564

Genes

KRAS
ARID1A
ATM
BRAF
BRCA1
CDKN2A
KDM6A
MYC
SMAD4
TP53

Provenance

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