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Association of SIRT1 rs3758391 Polymorphism With T2DM in Bangladeshi Population: Evidence From a Case‐Control Study and Meta‐Analysis

1 Feb 2025

Abstract excerpt

ABSTRACT Background and Aim Type 2 diabetes mellitus (T2DM) remains one of the major causes of morbidity and mortality worldwide, including Bangladesh. SIRT1, an NAD‐dependent deacetylase, is involved in energy homeostasis and protects β‐cells of the pancreas from oxidative stress. Single nucleotide polymorphisms (SNPs) in the SIRT1 gene have been found to be associated with T2DM in several populations, however,...

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PMID: 39980831
DOI: 10.1002/hsr2.70495

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