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Mimicking the Dystrophic Cardiac Extracellular Environment through DystroGel

17 Feb 2025

Abstract excerpt

Advances in understanding the mechanisms behind genetic diseases like Duchenne muscular dystrophy (DMD) underscore the critical role of the extracellular matrix (ECM) composition in disease progression. Effective in vitro models must replicate the intercellular relationships and physicochemical properties of native ECM to fully capture disease-specific characteristics. Although recent biomaterials support the in...

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PMID: 39962811
DOI: 10.1002/adhm.202404251

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