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Article

Regulatory mechanisms of connexin26.

Neuroscience - 27 Mar 2025

Ke Yihan, Liu Xiaozhou, Sun Yu

Abstract excerpt

Connexins are essential for cellular communication and play a critical role in various physiological processes, including hearing. Connexin26 (Cx26), encoded by the GJB2 gene, is a key component of cochlear gap junctions and is vital for potassium recycling and ATP release-both of which are vital for auditory function. Mutations in GJB2 are the primary cause of sensorineural hearing loss. However, the phenotypic...

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Identifiers

PMID: 39956354
DOI: 10.1016/j.neuroscience.2025.02.027

Genes

GJB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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