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Article

Connexins in hearing loss: a comprehensive overview.

Journal of basic and clinical physiology and pharmacology - 1 Jan 2005

Sabag Adi D, Dagan Orit, Avraham Karen B

Abstract excerpt

Connexins are a family of transmembrane proteins that form gap junctions between adjacent cells and allow intercellular communication. Connexin proteins are involved in pathological conditions in humans, mainly in hearing loss, neurodegenerative disorders and skin diseases. The association between connexin proteins and the inner ear is well established. The abundant expression of connexins in the auditory system...

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Identifiers

PMID: 16285463
DOI: 10.1515/jbcpp.2005.16.2-3.101

Genes

GJB2

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