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Article

Inner Ear Connexin Channels: Roles in Development and Maintenance of Cochlear Function.

Cold Spring Harbor perspectives in medicine - 1 Jul 2019

Mammano Fabio

Abstract excerpt

Connexin 26 and connexin 30 are the prevailing isoforms in the epithelial and connective tissue gap junction systems of the developing and mature cochlea. The most frequently encountered variants of the genes that encode these connexins, which are transcriptionally coregulated, determine complete loss of protein function and are the predominant cause of prelingual hereditary deafness. Reducing connexin 26...

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Identifiers

PMID: 30181354
DOI: 10.1101/cshperspect.a033233
PMCID: PMC6601451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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