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NeuralCodOpt: Codon optimization for the development of DNA vaccines.

Computational biology and chemistry - 1 Jun 2025

Chowdhury Tapan, Saha Aishwarya, Saha Ananya, Chakraborty Arnab, Das Nibir

Abstract excerpt

Inefficient gene translation, driven by organisms' codon preferences, is an emerging research area since this results in sluggish processes and diminished protein yields. Our research culminates in deriving efficient, optimized codon sequences by considering organism-specific Relative Codon Adaptiveness (RCA) ranges. In this research work, we have developed a novel algorithm, Neural Codon Optimization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39954612
DOI: 10.1016/j.compbiolchem.2025.108377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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