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Article

Single-Tube, Switched Temperature Amplicon Barcoding for Multiplex Detection of Rare Mutations in Circulating Tumor DNA.

The Journal of molecular diagnostics : JMD - 1 Apr 2025

Godfrey Tony E, Kintsurashvili Ekaterina, Rasic Gordana, Kaur Jessalyn, D'Amato Christopher, Meltzer Robert H

Abstract excerpt

Detection and analysis of circulating tumor DNA (ctDNA) as a biomarker for cancer is a promising approach. Applications for ctDNA analysis include screening, diagnosis, treatment selection, treatment monitoring, minimal residual disease detection, and recurrence monitoring. Detection of ctDNA is challenging and requires highly sensitive methods. Approaches such as digital PCR are appropriate when only a small...

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Share to Biomarkers, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Barcoding, Taxonomic

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Source

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Identifiers

PMID: 39952465
DOI: 10.1016/j.jmoldx.2025.01.004
PMCID: PMC11966241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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