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The bsh1 gene of Lactobacillus plantarum AR113 ameliorates liver injury in colitis mice

11 Feb 2025

Abstract excerpt

The Western diet (WD) leads to hepatic lipid metabolism disorders. Previous studies have shown that the bile salt hydrolase 1 (bsh1) gene of Lactobacillus plantarum AR113 attenuates colitis under WD. In this study, we preliminarily explored how AR113 attenuates the hepatic inflammatory response in colitis mice on the WD. Our study suggests that the WD leads to abnormalities in hepatic lipid metabolism and...

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PMID: 39934175
DOI: 10.1038/s41538-025-00373-3

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