Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation.

Scientific reports - 11 May 2017

Sheng Lili, Jena Prasant Kumar, Liu Hui-Xin, Kalanetra Karen M, Gonzalez Frank J, French Samuel W, Krishnan Viswanathan V, Mills David A, Wan Yu-Jui Yvonne

Abstract excerpt

This study aims to uncover how specific bacteria and bile acids (BAs) contribute to steatosis induced by diet and farnesoid X receptor (FXR) deficiency in both genders. A control diet (CD) and Western diet (WD), which contains high fat and carbohydrate, were used to feed wild type (WT) and FXR knockout (KO) mice followed by phenotyping characterization as well as BA and microbiota profiling. Our data revealed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Acids and Salts
Share to Diet, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dysbiosis

Share to Fatty Liver

Share to Glucose Tolerance Test

Share to Microbiota

Share to Receptors, Cytoplasmic and Nuclear

Share to Statistics, Nonparametric

Source

Open in PubMed Open full text

Identifiers

PMID: 28496104
DOI: 10.1038/s41598-017-01576-9
PMCID: PMC5431816

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation.PMID 28496104Read ↗

The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics studySemantic proximity Read ↗

Cross-talk between bile acids and intestinal microbiota in host metabolism and healthSemantic proximity Read ↗

Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota–Bile Acid AxisSemantic proximity Read ↗

Sex Differences in Gut Microbiome in High-Fat-Diet Fed RatsSemantic proximity Read ↗

Sex differences in gut microbiome in high-fat-diet fed rats.Semantic proximity Read ↗

Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesisSemantic proximity Read ↗

Regulation of bile acid metabolism-related signaling pathways by gut microbiota in diseasesSemantic proximity Read ↗

Bile acid metabolism in health and ageing-related diseasesSemantic proximity Read ↗

The gut microbiota at the intersection of bile acids and intestinal carcinogenesis: An old story, yet mesmerizingSemantic proximity Read ↗

Gut dysbiosis protects against liver injury in autophagy deficient mice by FXR-FGF15 feedback signalingSemantic proximity Read ↗

Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation.Semantic proximity Read ↗

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.