Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the causal relationship between five chosen factors and early-onset Alzheimer's disease: A Mendelian randomization study.

Journal of Alzheimer's disease : JAD - 1 Feb 2025

Lu Chunxin, Zhou Jiechao

Abstract excerpt

BACKGROUND: This study aims to explore the causal relationship between five selected factors-lysosome, migrasomes, macrophage, fibroblast, and endothelium cell-and early-onset Alzheimer's disease (EOAD) through related genes, providing clues for EOAD research. METHODS: Using genes related to the five selected factors as exposure variables and EOAD as the disease outcome, significant genes were screened through...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Fibroblasts
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Lysosomes

Share to Macrophages

Share to Mendelian Randomization Analysis

Share to Risk Factors

Source

Identifiers

PMID: 39924849
DOI: 10.1177/13872877241310248

Genes

LYST
NCF4
ADM
ANXA11
ARSB
CLN5
EPDR1
NFIB
NKTR
PYGB
SORT1
SYNGR1
VIPAS39

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the causal relationship between five chosen factors and early-onset Alzheimer's disease: A Mendelian randomization study.PMID 39924849Read ↗

Systematic evaluation of multifactorial causal associations for Alzheimer's disease and an interactive platform based on Mendelian randomization analysis——MRADSemantic proximity Read ↗

Causality relationship between 91 inflammatory factors and Alzheimer disease: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

Systematic evaluation of multifactorial causal associations for Alzheimer's disease and an interactive platform MRAD developed based on Mendelian randomization analysis.Semantic proximity Read ↗

Five Major Psychiatric Disorders and Alzheimer's Disease: A Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

Causal Relationship between Inflammatory Proteins and Alzheimer's Disease: A Two-Sample Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

AlzRiskMR database: an online database for the impact of exposure factors on Alzheimer's disease.Semantic proximity Read ↗

Emerging risk of environmental factors: insight mechanisms of Alzheimer’s diseasesSemantic proximity Read ↗

Exploring the bidirectional relationships between alzheimer's disease and cerebral small vessel disease: Insights from mendelian randomizationSemantic proximity Read ↗

[Plasma metabolites mediates the causal effect of inflammatory proteins on Alzheimer's disease: a Mendelian randomization study].Semantic proximity Read ↗

The relationship between Alzheimer's disease and intracerebral hemorrhage based on Mendelian randomization.Semantic proximity Read ↗

Mendelian randomization study of genetic interactions between Alzheimer disease and celiac disease.Semantic proximity Read ↗

The relationship between Alzheimer disease and thyroiditis: A two-sample Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.