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Article

The role of candidate genetic polymorphisms in covid-19 susceptibility and outcomes.

BMC medical genomics - 7 Feb 2025

Yazbeck Anthony, Akika Reem, Awada Zainab, Zgheib Nathalie K

Abstract excerpt

BACKGROUND: This study aims to investigate the association between candidate host genetic polymorphisms and COVID-19 susceptibility, severity, hospitalization, hypoxia, and their combined effect, measured by the polygenic risk score (PRS). METHODS: Three hundred and seventy-six Lebanese participants, comprising 151 controls and 225 cases, were included. Clinical data were obtained from questionnaires and medical...

Read the complete abstract on PubMed

Topics

Polymorphism, Genetic
COVID-19
Treatment Outcome
Genetic Predisposition to Disease
Genetic Risk Score
Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Severity of Illness Index

Hospitalization

Hypoxia

Source

Open in PubMed Open full text

Identifiers

PMID: 39920651
DOI: 10.1186/s12920-025-02094-8
PMCID: PMC11806658

Genes

TMPRSS2
ACE2
OAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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