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Article

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients

15 Jan 2025

Abstract excerpt

Rationale: COVID-19-associated acute-respiratory distress syndrome (C-ARDS) results from a direct viral injury associated with host excessive innate immune response mainly affecting the lungs. However, cytokine profile in the lung compartment of C-ARDS patients has not been widely studied, nor compared to non-COVID related ARDS (NC-ARDS). Objectives: To evaluate caspase-1 activation, IL-1 signature, and other...

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Identifiers

PMID: 39882243
DOI: 10.3389/fimmu.2024.1493306

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