Article
Statistical analysis plan for hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock: the ANDROMEDA-SHOCK-2 randomized clinical trial.
Critical care science - 1 Jan 2025
Orozco Nicolas, García-Gallardo Gustavo, Cavalcanti Alexandre Biasi, Santos Tiago Mendonça Dos, Ospina-Tascón Gustavo, Bakker Jan, Morales Sebastián, Ramos Karla, Alegria Leyla, Teboul Jean Louis, Backer Daniel De, Vieillard-Baron Antoine, Fernandez Liliana Vallecilla, Lima Lucas Martins de, Damiani Lucas Petri, Sady Erica Ribeiro, Santucci Eliana Vieira, Hernandez Glenn, Kattan Eduardo
Abstract excerpt
BACKGROUND: ANDROMEDA-SHOCK 2 is an international, multicenter, randomized controlled trial comparing hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock to standard care resuscitation to test the hypothesis that the former is associated with lower morbidity and mortality in terms of hierarchal analysis of outcomes. OBJECTIVE: To report the statistical plan for the...
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