Article
Associations between common genetic variants and income provide insights about the socio-economic health gradient.
Nature human behaviour - 1 Apr 2025
Kweon Hyeokmoon, Burik Casper A P, Ning Yuchen, Ahlskog Rafael, Xia Charley, Abner Erik, Bao Yanchun, Bhatta Laxmi, Faquih Tariq O, de Feijter Maud, Fisher Paul, Gelemanović Andrea, Giannelis Alexandros, Hottenga Jouke-Jan, Khalili Bita, Lee Yunsung, Li-Gao Ruifang, Masso Jaan, Myhre Ronny, Palviainen Teemu, Rietveld Cornelius A, Teumer Alexander, Verweij Renske M, Willoughby Emily A, Agerbo Esben, Bergmann Sven, Boomsma Dorret I, Børglum Anders D, Brumpton Ben M, Davies Neil Martin, Esko Tõnu, Gordon Scott D, Homuth Georg, Ikram M Arfan, Johannesson Magnus, Kaprio Jaakko, Kidd Michael P, Kutalik Zoltán, Kwong Alex S F, Lee James J, Luik Annemarie I, Magnus Per, Marques-Vidal Pedro, Martin Nicholas G, Mook-Kanamori Dennis O, Mortensen Preben Bo, Oskarsson Sven, Pedersen Emil M, Polašek Ozren, Rosendaal Frits R, Smart Melissa C, Snieder Harold, van der Most Peter J, Vollenweider Peter, Völzke Henry, Willemsen Gonneke, Beauchamp Jonathan P, DiPrete Thomas A, Linnér Richard Karlsson, Lu Qiongshi, Morris Tim T, Okbay Aysu, Harden K Paige, Abdellaoui Abdel, Hill W David, de Vlaming Ronald, Benjamin Daniel J, Koellinger Philipp D
Abstract excerpt
We conducted a genome-wide association study on income among individuals of European descent (N = 668,288) to investigate the relationship between socio-economic status and health disparities. We identified 162 genomic loci associated with a common genetic factor underlying various income measures, all with small effect sizes (the Income Factor). Our polygenic index captures 1-5% of income variance, with only one...
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