Article
One class classification-empowered radiomics for noninvasively accurate prediction of glioma isocitrate dehydrogenase mutation using multiparametric magnetic resonance imaging.
Clinical radiology - 1 May 2025
Jian J, Xu L, Gong C, Ding S, Gong X, Yuan X, Zheng W, Wang X, Zhang Y
Abstract excerpt
BACKGROUND: Noninvasive detection of isocitrate dehydrogenase (IDH) mutations is crucial for preoperative decision-making in patients with glioma. While radiomics has been applied, data imbalance-specifically between IDH wild-type and mutated genes-remains underexplored. We developed a one-class classification-empowered radiomics (OCCR) model, trained exclusively on IDH wild-type patients, to distinguish them...
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