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Migrasomes trigger innate immune activation and mediate transmission of senescence signals across human cells

1 Dec 2023

Abstract excerpt

Aging is a complex and heterogeneous process, raising important questions about how aging is differently impacted by underlying genetics and external factors. Recently, migrasomes, newly discovered organelles, have been identified to play important roles in various physiological and pathological processes by facilitating cell-to-cell communication. Thus far, their involvement in cellular senescence and aging...

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PMID: 39872064
DOI: 10.1093/lifemedi/lnad050

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