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Article

Tau therapeutics for Alzheimer's disease: the promise and the challenges.

Journal of molecular neuroscience : MN - 1 Dec 2002

Gold Michael

Abstract excerpt

The pathological diagnosis of Alzheimer's disease (AD) depends on the presence of plaques consisting of the beta-amyloid peptide as well as neurofibrillary tangles consisting of paired helical filaments (PHFs) of the tau (tau) protein. The role of each type of pathology in the pathogenesis and progression of AD remains unclear. Previous hypotheses suggested that these two processes were independent, whereas more...

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Identifiers

PMID: 12540060
DOI: 10.1385/jmn:19:3:329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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