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Article

Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course.

Frontiers in immunology - 1 Jan 2024

Zucchi Elisabetta, Banchelli Federico, Simonini Cecilia, De Biasi Sara, Martinelli Ilaria, Gianferrari Giulia, Lo Tartaro Domenico, Cossarizza Andrea, D'Amico Roberto, Mandrioli Jessica

Abstract excerpt

Introduction: T regulatory cells (Tregs) inversely correlate with disease progression in Amyotrophic Lateral Sclerosis (ALS) and fast-progressing ALS patients have been reported to exhibit dysfunctional, as well as reduced, levels of Tregs. This study aimed to evaluate the longitudinal changes in Tregs among ALS patients, considering potential clinical and biological modifiers of their percentages and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39845951
DOI: 10.3389/fimmu.2024.1508974
PMCID: PMC11750661

Genes

CD38
CD4
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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