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Article

Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice.

Physiological reports - 1 Jan 2025

Faizan Md Imam, Kaur Gagandeep, Shaikh Sadiya Bi, Effah Felix, Unwalla Hoshang, Rahman Irfan

Abstract excerpt

The use of genetically diverse mouse models offers a more accurate reflection of human genetic variability, improving the translatability of findings to heterogeneous human populations. This approach is particularly valuable in understanding diverse immune responses to disease by environmental exposures. This study investigates the inflammatory responses to acute exposures to mainstream cigarette smoke (CS) and...

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Topics

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Share to Bronchoalveolar Lavage Fluid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophages, Alveolar

Share to Matrix Metalloproteinase 12

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Source

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Identifiers

PMID: 39844449
DOI: 10.14814/phy2.70199
PMCID: PMC11754243

Genes

CS
MMP12
MMP9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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