Article
Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomization.
Cardiovascular diabetology - 22 Jan 2025
Zhao Xiaoxiao, Li Jiannan, Yan Shaodi, Tan Yu, Chen Runzhen, Li Nan, Zhou Jinying, Liu Chen, Zhou Peng, Chen Yi, Yan Hongbing, Zhao Hanjun, Song Li
Abstract excerpt
AIM: Both clonal hematopoiesis of indeterminate potential (CHIP) and type 2 diabetes mellitus (T2DM) are conditions closely associated with advancing age. This study delves into the possible implications and prognostic significance of CHIP and T2DM in patients diagnosed with ST-segment elevation myocardial infarction (STEMI). METHODS: Deep-targeted sequencing employing a unique molecular identifier (UMI) for the...
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