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Modelling host–pathogen interactions: Galleria mellonella as a platform to study Pseudomonas aeruginosa response to host-imposed zinc starvation

21 Jan 2025

Abstract excerpt

Nutritional immunity, a key component of the vertebrate innate immune response, involves the modulation of zinc availability to limit the growth of pathogens. Pseudomonas aeruginosa counteracts host-imposed zinc starvation through metabolic adaptations, including reprogramming of gene expression and activating efficient metal uptake systems. To unravel how zinc shortage contributes to the complexity of bacterial...

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PMID: 39841126
DOI: 10.1099/mic.0.001524

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