Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATF3 triggers M2 macrophage polarization to protect against pulp inflammation through WNT4 regulation

9 Jan 2025

Abstract excerpt

Pulpitis is a common inflammatory oral disease that can lead to pulp necrosis. The aim of this study is to investigate the expression and regulatory mechanisms of ATF3, a potential therapeutic marker, in pulpitis. A mouse pulpitis model with different degrees of inflammation is established, and the expression of ATF3 in pulpitis is explored. The histological features of healthy pulp and pulpitis are analyzed by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to Periodontal Regeneration and Treatments
Share to Wound Healing and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39801194
DOI: 10.3724/abbs.2025005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATF3 triggers M2 macrophage polarization to protect against pulp inflammation through WNT4 regulationPMID 39801194Read ↗

Dysregulation of lncRNA GATA3-AS1 is Involved in the Pathogenesis of Pulpitis by the Regulation of miR-17-3pSemantic proximity Read ↗

Osteopontin interacts with dendritic cells and macrophages in pulp inflammation: Comprehensive transcriptomic analysis and laboratory investigationsSemantic proximity Read ↗

Stathmin regulates the proliferation and differentiation of inflammatory hDPSCs through canonical Wnt/β-catenin pathwaySemantic proximity Read ↗

Effects of miR-629-5p on odontoblast differentiation and target gene TEAD4 expression of dental pulp stem cellsSemantic proximity Read ↗

ATF3 promotes migration and M1/M2 polarization of macrophages by activating tenascin‑C via Wnt/β‑catenin pathway.Semantic proximity Read ↗

The Dual Roles of Activating Transcription Factor 3 (ATF3) in Inflammation, Apoptosis, Ferroptosis, and Pathogen Infection ResponsesSemantic proximity Read ↗

Identification of Pulpitis-Related Potential Biomarkers Using Bioinformatics ApproachSemantic proximity Read ↗

Using Spatial Transcriptomics to Identify a Diagnostic Molecular Signature Associated with Reversible Dental PulpitisSemantic proximity Read ↗

IFN-γ regulates human dental pulp stem cells behavior via NF-κB and MAPK signaling.Semantic proximity Read ↗

ATF2 orchestrates macrophage differentiation and activation to promote antibacterial responsesSemantic proximity Read ↗

Combined Transcriptomic and Proteomic Profiling of the Mouse Anterior Cingulate Cortex Identifies Potential Therapeutic Targets for Pulpitis-Induced PainSemantic proximity Read ↗

RNA sequencing reveals key factors modulating TNFα-stimulated odontoblast-like differentiation of dental pulp stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.