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Article

Exploring associations between the FTO rs9939609 genotype and plasma concentrations of appetite-related hormones in adults with obesity.

PloS one - 1 Jan 2025

de Soysa Ann Kristin Hjelle, Langaas Mette, Grill Valdemar, Martins Catia, Løvold Mostad Ingrid

Abstract excerpt

Associations between variants in the FTO locus and plasma concentrations of appetite related hormones are inconsistent, and might not work in a dose dependent fashion in people with obesity. Moreover, it is relevant to report meal related plasma concentrations of these hormones in persons with obesity given the growing interest in their pharmacological potential in obesity therapy. We find it clinically relevant...

Read the complete abstract on PubMed

Topics

Humans
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Female
Male
Adult
Obesity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Ghrelin

Peptide YY

Glucagon-Like Peptide 1

Middle Aged

Genotype

Polymorphism, Single Nucleotide

Appetite

Cross-Sectional Studies

Body Mass Index

Source

Open in PubMed Open full text

Identifiers

PMID: 39792913
DOI: 10.1371/journal.pone.0312815
PMCID: PMC11723609

Genes

PYY
FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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Exploring associations between the FTO rs9939609 genotype and plasma concentrations of appetite-related hormones in adults with obesity.PMID 39792913Read ↗

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FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.Semantic proximity Read ↗

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FTO genotypes (rs9939609 T>A) are Associated with Increased Added Sugar Intake in Healthy Young Adults.Semantic proximity Read ↗

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