Article
Obesity associated genetic variation in FTO is associated with diminished satiety.
The Journal of clinical endocrinology and metabolism - 1 Sept 2008
Wardle Jane, Carnell Susan, Haworth Claire M A, Farooqi I Sadaf, O'Rahilly Stephen, Plomin Robert
Abstract excerpt
CONTEXT: Polymorphisms within the FTO gene have consistently been associated with obesity across multiple populations. However, to date, it is not known whether the association between genetic variation in FTO and obesity is mediated through effects on energy intake or energy expenditure. OBJECTIVE: Our objective was to examine the association between alleles of FTO known to increase obesity risk and measures of...
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