Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluating TAB2, IKBKB, and IKBKG Gene Polymorphisms and Serum Protein Levels and Their Association with Age-Related Macular Degeneration and Its Treatment Efficiency.

Medicina (Kaunas, Lithuania) - 16 Dec 2024

Vilkeviciute Alvita, Pileckaite Enrika, Bruzaite Akvile, Cebatoriene Dzastina, Gedvilaite-Vaicechauskiene Greta, Kriauciuniene Loresa, Zaliuniene Dalia, Liutkeviciene Rasa

Abstract excerpt

Background and Objectives: Age-related macular degeneration (AMD) is the leading cause of blindness, affecting millions worldwide. Its pathogenesis involves the death of the retinal pigment epithelium (RPE), followed by photoreceptor degeneration. Although AMD is multifactorial, various genetic markers are strongly associated with the disease and may serve as biomarkers for evaluating treatment efficacy. This...

Topics

Join the communities discussing this publication.

Adaptor Proteins, Signal Transducing
Aged
Aged, 80 and over
Biomarkers
Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

I-kappa B Kinase

Macular Degeneration

Treatment Outcome

Source

Identifiers

PMID: 39768951
DOI: 10.3390/medicina60122072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluating TAB2, IKBKB, and IKBKG Gene Polymorphisms and Serum Protein Levels and Their Association with Age-Related Macular Degeneration and Its Treatment Efficiency.PMID 39768951Read ↗

The Impact of ARMS2 (rs10490924), VEGFA (rs3024997), TNFRSF1B (rs1061622), TNFRSF1A (rs4149576), and IL1B1 (rs1143623) Polymorphisms and Serum Levels on Age-Related Macular Degeneration Development and Therapeutic Responses.Semantic proximity Read ↗

Exudative Age-Related Macular Degeneration: Association between Treatment Efficacy and Single-Nucleotide Variants in RAD51B, TRIB1, COL8A1, COL10A1, IL-9, IL-10, and VEGFA Genes.Semantic proximity Read ↗

VEGFA Haplotype and VEGF-A and VEGF-R2 Protein Associations with Exudative Age-Related Macular Degeneration.Semantic proximity Read ↗

Evaluation of serum SLCO1B1 levels and genetic variants of SLCO1B1 rs4149056 and rs2306283 in patients with early and exudative age-related macular degeneration.Semantic proximity Read ↗

Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.Semantic proximity Read ↗

Next-generation sequencing analysis of the ARMS2 gene in Turkish exudative age-related macular degeneration patients.Semantic proximity Read ↗

Uncovering genetic and non-genetic biomarkers specific for exudative age-related macular degeneration: significant association of twelve variantsSemantic proximity Read ↗

Genetic variants and serum biomarkers of CXCL8, MAP3K7, LTA/TNF, EXOC3L1, PROCR, and TRAF2 in Age-Related macular degeneration: associations with disease risk and therapeutic response.Semantic proximity Read ↗

Associations of cholesteryl ester transfer protein (CETP) gene variants with predisposition to age-related macular degeneration.Semantic proximity Read ↗

The Role of SNPs in IL1RL1 and IL1RAP Genes in Age-related Macular Degeneration Development and Treatment Efficacy.Semantic proximity Read ↗

Evaluation of clinical and genetic indicators for the early response to intravitreal ranibizumab in exudative age-related macular degeneration.Semantic proximity Read ↗

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networksSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.